Ulcerative colitis (UC) is a chronic non-specific intestinal disease with lesions involving the rectum and colon, and clinical manifestations include abdominal pain, diarrhea, and muco-purulent and bloody stools. In recent years, the incidence of UC has surged, which seriously affects the quality of life of patients. The pathogenesis of ulcerative colitis is complex and diverse, involving environmental factors, genetic factors, body immunity and psychological factors. In order to deeply investigate the pathogenesis and regulatory mechanism of this disease and develop targeted therapeutic drugs, it is particularly important to construct suitable animal experimental models. In this paper, we summarize the current selection of animals inducing ulcerative colitis, modeling methods, and model evaluation indexes, in order to provide more feasible solutions for scientific research experiments and clinical practice, and at the same time to provide reference for researchers in related fields to follow up the researchers.