
神经药理学报››2015,Vol. 5››Issue (6): 51-56.
胡宝玲, 郭春燕
出版日期:2015-12-26发布日期:2016-03-03通讯作者:郭春燕,女,教授,硕士研究生导师;研究方向:神经药理学,药物分析;E-mail:18931316689@163.com作者简介:胡宝玲,女,硕士研究生;研究方向:神经药理学;E-mail:hubaoling2014@163.com基金资助:
河北省教育厅重大项目(No.ZD2014075)
HU Bao-ling, GUO Chun-yan
Online:2015-12-26Published:2016-03-03Contact:郭春燕,女,教授,硕士研究生导师;研究方向:神经药理学,药物分析;E-mail:18931316689@163.comAbout author:胡宝玲,女,硕士研究生;研究方向:神经药理学;E-mail:hubaoling2014@163.comSupported by:
河北省教育厅重大项目(No.ZD2014075)
摘要:芍药苷(paeoniflorin,PF)是芍药的主要有效成分,具有多种药理作用。本文从调节自噬、调节免疫、抑制炎症因子产生、调节钙离子、钾离子通道、阻断酸敏感离子通道、调节MAPK、PI3K/Akt、Nrf2/ARE信号转导通路、对抗神经毒性、激活2型大麻素受体、抗氧化应激、抑制神经细胞凋亡等方面综述芍药苷的神经保护作用。
中图分类号:
胡宝玲, 郭春燕.芍药苷神经保护作用机制的研究进展[J]. 神经药理学报, 2015, 5(6): 51-56.
HU Bao-ling, GUO Chun-yan.Advances Achievements about Neuroprotective Mechanisms of Paeoniflorin[J]. ACTA NEUROPHARMACOLOGICA, 2015, 5(6): 51-56.
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