神经药理学报››2014,Vol. 4››Issue (1): 25-28.
刘婷婷，王文
出版日期:2014-02-26发布日期:2014-06-06通讯作者:王文，男，教授，博士，研究生导师；研究方向：神经药理，中药药理；E-mail:lzwwang@163.com作者简介:刘婷婷，女，硕士研究生；研究方向：神经药理，中药药理；E-mail:liuting_416@126.com基金资助:
“重大新药创制”科技重大专项(No.2012ZX09102-201-016)，国家自然科学基金(No.81173575\81373994)，北京市自然科学基金(No.7062031)，北京市教委科技创新平台项目(No.111219)，2011年北京市卫生系统高层次卫生技术星空娱乐app最新版计划项目（No.2011-3-097)，第52批中国博士后基金(No.106455)
LIU Ting-ting, WANG Wen
Online:2014-02-26Published:2014-06-06Contact:王文，男，教授，博士，研究生导师；研究方向：神经药理，中药药理；E-mail:lzwwang@163.comAbout author:刘婷婷，女，硕士研究生；研究方向：神经药理，中药药理；E-mail:liuting_416@126.comSupported by:
“重大新药创制”科技重大专项(No.2012ZX09102-201-016)，国家自然科学基金(No.81173575\81373994)，北京市自然科学基金(No.7062031)，北京市教委科技创新平台项目(No.111219)，2011年北京市卫生系统高层次卫生技术星空娱乐app最新版计划项目（No.2011-3-097)，第52批中国博士后基金(No.106455)
摘要：Eph/ephrin是目前已知的具有最多成员的蛋白受体酪氨酸激酶家族，在机体的发育过程中参与细胞迁移、轴突导向、血管形成及神经网络的形成，对成年中枢神经系统的神经再生和突触可塑性具有重要作用。通过激活或抑制Eph/ephrin可调节损伤后的突触功能和干细胞分化，达到修复梗死灶、改善神经功能缺失的目的。本文对Eph/ephrin信号通路在成年动物海马区、室管膜下区及非传统神经发生区域内调节神经发生、迁移以及突触可塑性作用的研究进展进行综述，将对探索有效的神经损伤修复方法有一定的提示作用。
刘婷婷, 王文.Eph/ephrin信号通路与脑神经发生的综述[J]. 神经药理学报, 2014, 4(1): 25-28.
LIU Ting-ting, WANG Wen.Eph/ephrin Signaling Pathway in Brain Neurogenesis[J]. ACTA NEUROPHARMACOLOGICA, 2014, 4(1): 25-28.
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