Objective：To analyze the clinical efficacy of Jianzhong Yuyang tablet in the treatment of gastrointestinal ulcer bleeding and its influence on gastroenteric electroencephalogram. Methods： A total of 106 patients with gastrointestinal ulcer bleeding treated in our hospital from August 2021 to August 2023 were selected and divided into 2 groups according to different treatment methods. 52 cases in the comparison group were given conventional symptomatic treatment with Western medicine，and 54 cases in the observation group were given Jianzhong Yuyang tablet on the basis of the comparison group. The clinical efficacy，pH value of gastric fluid， hemoglobin （Hb）， electrogastroenterogram and serum inflammatory factors were compared between the two groups. Results： The total clinical effective rate of observation group（ 96.30%） was higher than that of comparison group（ 76.92%）（ P<0.05）. After treatment，the pH and Hb of gastric juice in observation group were higher than those in comparison group （P<0.05）. After treatment， the average amplitude of stomach body， gastric antrum， transverse colon， descending colon and rectum in observation group was higher than that in comparison group （P<0.05）. The levels of hypersensitive C-reactive protein （hs-CRP）， interleukin-10 （IL-10） and IL-8 in the observation group after treatment were lower than those in the control group （P<0.05）. Conclusion： Jianzhong Yuyang Tablet can effectively improve the symptoms of ulcer and bleeding in patients with gastrointestinal ulcer hemorrhage， increase Hb， regulate gastroenteric electroencephalogram， and reduce inflammation.