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%A JIA Zhen-jie, YANG Xin-ming, DING Peng-hui %T Research Progress on Anti-Inflammatory Drugs and Lumbar Intervertebral Disc Herniation %0 Journal Article %D 2021 %J ACTA NEUROPHARMACOLOGICA %R 10.3969/j.issn.2095-1396.2021.04.010 %P 58- %V 11 %N 4 %U {http://actanp.hebeinu.edu.cn/CN/abstract/article_777.shtml} %8 2021-08-26 %X
Low back pain caused by lumbar intervertebral disc herniation
（
LDH
）
is closely related to inflammation. Inflammatory factors stimulate nerve fibers may cause pain
，
which is also one of the reasons for the degeneration of the intervertebral disc. At present
，
there is a lack of stable and reliable anti-inflammatory drugs for lumbar disc herniation. The inflammatory mechanism and related signal pathways of lumbar disc herniation were reviewed. According to theoretical laboratory research or ongoing clinical trials
，
steroidal anti-inflammatory drugs
，
non-steroidal anti-inflammatory drugs
，
Chinese medicines
，
growth factors and cytokines were analyzed. A batch of potential anti-inflammatory drugs
，
hoping to provide reference and reference for the selection of anti-inflammatory drugs and follow-up treatment for LDH clinical treatment.