Rheumatoid arthritis（RA） is a common autoimmunedisease in rheumatology department with unknown etiology.Currently，non steroidal anti-inflammatory drugs，hormones and immunosuppressants are the main treatment options in clinic.Although the symptoms improve rapidly，there are many side effects（such as gastrointestinal reactions，liver and kidney function damage，etc.），and it is easy to relapse，which limits the follow-up treatment of patients.Therefore，it is urgent to find safe and effective drugs.In recent years，a large number of studies have shown that single Chinese medicine extract has obvious advantages in the prevention and treatment of rheumatoid arthritis.This paper reviews the mechanism of single Chinese medicine extract in the treatment of rheumatoidarthritis，in order to provide reference for the experimental research and clinical application of rheumatoid arthritis.