Objective：To explore the research progress of lidocaine transdermal preparations and provide references for the preparation of new，safe and efficient transdermallocal anesthetic preparations required for clinical treatment. Methods：The relevant literatures

of lidocaine transdermal preparations at home and abroad were searched in recent years，and the main dosage forms and characteristics of the transdermal preparations were reviewed. Results： Lidocaine transdermal preparations can increase the transdermal rate，have a rapid onset of action，improve bioavailability，and reduce adverse reactions. The currently retrieved lidocaine dosage forms include creams，gels and other traditional preparations and microemulsions，microemulsion gels，liposomes，alcohol liposomes，film sprays，cataplasms，mesoporous silica nanoparticles. The particles are loaded with new carrier dosage forms such as lidocaine. Conclusion：With the development of new transdermal dosage forms and new technologies， the research results of lidocaine transdermal preparations are expected to be used safely and efficiently in the future.