Objective：To compare the analgesic effects of Corydalis Yanhusuo，Radix Lindera，Jin Ling-zi powder and Xiao Huo-luo Dan on chronic neuropathic pain in rats with sciatic nerve chronic constriction injury （CCI）. Methods：The male SD rats were randomly divided into 6 groups，sham operation group （n=13），saline group （n=13），Corydalis Yanhusuo group （n=16）， Radix Lindera group （n=10），Jin Ling-zi powder group （n=20） and Xiao Huo-luo Dan group （n=7），respectively. Four days after the CCI surgery，the drugs were given by intragastric administration. The rats in Corydalis Yanhusuo group，Radix Lindera group，Jin Ling-zi powder group and Xiao Huo-luo Dan group were given 12 g·kg-1 drug respectively. The sham operation group and saline group were given the same amount of saline. The rats were administered intragastrically once a day for 14 consecutive days. From the beginning of the administration，the threshold of thermal pain was measured every other day by hot needling instrument. Results：Compared with Control group，the thermal threshold of Corydalis Yanhusuo group，Radix Lindera group，Jin Ling-zi powder group and Xiao Huo-luo Dan group were all increased，but the increase of Corydalis Yanhusuo group and Jin Ling-zi powder group were more significantly. Conclusion：Corydalis Yanhusuo，Radix Lindera，Jin Ling-zi powder and Xiao Huo-luo Dan all have analgesic effect on neuropathic pain，among which Jin Ling-zi powder has the strongest analgesic effect and the

fastest curative effect，followed by Corydalis Yanhusuo. The analgesic effects of Radix Lindera and Xiao Huo-luo Dan were not stable.