|星空彩票电脑版
%A ZHANG Li-na，ZHANG Xin，XUE Juan，ZHANG Dan-shen %T
Advances Achievements of Traditional Chinese Medicine on the Signaling Pathways in Central Nervous Degenerative Diseases%0 Journal Article %D 2017 %J ACTA NEUROPHARMACOLOGICA %R 10.3969/j.issn.2095-1396.2017.03.005 %P 33-42 %V 7 %N 3 %U {http://actanp.hebeinu.edu.cn/CN/abstract/article_467.shtml} %8 2017-06-26 %X It is found that Chinese medicine play a important role in the prevention and treatment of the central nervous system diseases（AD，PD，cerebral ischemia，etc） by adjusting the key signaling molecule such as Wnt，β-catenin，TCF/LEF，PI3K，AKT，mTOR，NF-κB，Cyt-C，Bcl-2 family，Caspases enzyme，etc，along with in-depth study of the pathogenesis on Chinese medicine used to delay aging and prevent age-related diseases. This article focuses on three signaling pathways （Wnt/β-catenin，PI3K/Akt，mitochondrial apoptosis） and reviews the prevention and treatment of Chinese medicine on the central nervous system degenerative diseases mainly.