|星空彩票电脑版
%A HU Bao-ling, GUO Chun-yan %T
Advances Achievements about Neuroprotective Mechanisms of Paeoniflorin%0 Journal Article %D 2015 %J ACTA NEUROPHARMACOLOGICA %R %P 51-56 %V 5 %N 6 %U {http://actanp.hebeinu.edu.cn/CN/abstract/article_312.shtml} %8 2015-12-26 %X Paeoniflorin (paeoniflorin, PF) is one of the main effective components of herbaceouspeony with many kinds of pharmacologic effect. This article reviews the neuroprotective effect of paeoniflorin in the following several aspects: regulate autophagy, regulate immunity, inhibit inflammatory cytokines, adjust Ca2+, K+ channels, block acid-sensing ion channels, adjust MAPK、PI3K/Akt、Nrf2/ARE signal pathways, against neurotoxicity, activate cannabinoid receptor 2, antioxidant stress, inhibit neuron cells apoptosis.