|星空彩票电脑版
%A WANG Xiao-ru，AN Fang %T
Mechanism of Action of Autophagy on the Cerebral Ischemia-Reperfusion Injury%0 Journal Article %D 2016 %J ACTA NEUROPHARMACOLOGICA %R 10.3969/j.issn.2095-1396.2016.01.006 %P 41-48 %V 6 %N 1 %U {http://actanp.hebeinu.edu.cn/CN/abstract/article_290.shtml} %8 2016-02-26 %X Autophagy is a life phenomenon widely existing in eukaryotic cells and a special metabolic pathway of decomposition. It controls the degradation of protein and organelles and is essential for cell survival and tissue homeostasis. At present，autophagy has become a hot research topic in the field of biological medicine，and the studies have demonstrated the association with various diseases. To date，ischemic cerebral stroke responsible for human death and disability may cause the ischemia-reperfusion （I/R） injury，which is common and receives much more concern. This review states autophagy and its mechanisms on the I/R injury to provide the theoretical basis for further therapy on ischemic cerebrovascular disorder.