|星空彩票电脑版
%A ZHENG Qian-nan, HE Xin, SHI Song-li, ZHOU Hong-bin, WU Pei-sai %T
Effect of the Petroleum Ether Extract From Amygdalus Mongolica on Blood Lipid Level in Hyperlipidemia Rats%0 Journal Article %D 2015 %J ACTA NEUROPHARMACOLOGICA %R %P 12-16 %V 5 %N 3 %U {http://actanp.hebeinu.edu.cn/CN/abstract/article_262.shtml} %8 2015-06-26 %X
Objective：To study the effect of the petroleum ether extract from Amygdalus mongolica on blood lipid level in hyperlipidemia rats.
Methods：Model was established by feeding high-fat diet for five weeks. Experimental animals were divided into six groups：control group，model group，XUE Zhi-kang group（61.7 mg·kg-1）and 1 000，2 000，2 500 mg·kg-1 of the petroleum ether extract from Amygdalus mongolica. Hyperlipidemic indicators were tested after 7 weeks oral administration of petroleum ether extract. Lipid comprehensive index and atherosclerosis index were calculated.
Results：Compared with the hyperlipidemic model group，low-dose group of petroleum ether extract group from Amygdalus mongolica could significantly decreased the level of serum TC、LDL-C in the hyperlipidemia rat and TC/HDL-C、LDL-C/HDL-C、atherosclerotic index （P<0.01，P<0.05）.
Conclusion：Petroleum ether extract from Amygdalus mongolica could improve blood lipid level，reduced the risk of arteriosclerosis.