|星空彩票电脑版
%A WEI Wei， YUAN Yu-he， CHEN Nai-hong %T
The Effect of Microglial Cells on Parkinson’s Diseases%0 Journal Article %D 2012 %J ACTA NEUROPHARMACOLOGICA %R %P 28-31 %V 2 %N 4 %U {http://actanp.hebeinu.edu.cn/CN/abstract/article_118.shtml} %8 2012-08-26 %X Microglial cells play an essential role in degenerative neurological diseases, including neurodegenerative process of Alzheimer's disease and Parkinson's disease. However, it is yet unclear the exact roles of microglia cells in neurodegenerative diseases plays, although it is known that excessive activation of microglia will ultimately lead to neuronal death. Activated microglia secrete a variety of inflammatory and neurotoxic factors that may aggrevate neurodegenerative diseases. In fact, systemic inflammation is one of the main causes attributable to chronic neurodegenerative diseases related functions decline. In this article, we summarized the role of microglial cells in the pathogenesis of neurodegenerative diseases. In addition, we also discussed new methods and potential therapeutic strategies of neurodegenerative disorders.