Objective: To search Chinese medicine prescriptions containing chinemys reevesii in the database of pharmaceutical intelligence network, and analyze the compatibility of chinemys reevesii to provide reference for its application and development. Methods: Using Microsoft Office Excel 2021, IBM SPSS Modeler 18.0, and IBM SPSS Statistics 23.0, the main therapeutic indications of prescriptions the frequency of use, meridian tropism, and efficacy attribution of Chinese medicines were analyzed, the association rule analysis, cluster analysis, factor analysis and visualization display were also carried out. Results: 139 prescriptions are used to treat 24 kinds of diseases, mainly including liver and kidney yin deficiency syndrome, Chong and Ren disorder disease, mental fatigue disease, and stroke disease. 318 kinds of Chinese medicine in the formula composition, the most commonly used medicine were tonic herbs. The medicine nature is mainly warm, the tastes are mostly sweet, entering liver meridian and kidney meridian. Among the 31 association rules of 22 high-frequency Chinese medicine, the most supported pair medicines combination is“chinemys reevesii-angelica sinensis”, and Triangular medicines combination is“chinemys reevesii-radix rehmanniae preparata-angelica sinensis”, the four medicines combination are“chinemys reevesii-atractylodes macrocephala-radix rehmanniae preparata-angelica sinensis”. 22 high-frequency Chinese medicines can be divided into 4 classes, and 5 factors are extracted. Conclusion: Chinemys reevesii is often combined with tonic herbs with sweet and warm nature, which enters the liver and kidney meridians to treat TCM deficiency diseases such as liver and kidney yin deficiency syndrome, Chong and Ren disorder disease.