The research progress of atorvastatin in the treatment of type-2 diabetes mellitus complicated with coronary heart disease was reviewed. The impacts of different doses of atorvastatin on curative effect were introduced and the short-term efficacy of atorvastatin，simvastatin and rosuvastatin was compared and the first two former was better than that of the last. Atorvastatin in combination with an antihypertensive agent such as telmisartan，benazepril， lisinopril，or vigliptin enhances efficacy and improves safety. A combination of atorvastatin with Yangyin Huoxue decoction，or Dengzhan Xixin injection，or Xuefu Zhuyu tablet，or Jiangzhi Tongmai Capsules，or Tongxinluo capsule or Ezetimibucan also enhance the efficacy，improve safety and reduce the incidence of adverse events.