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摘要/Abstract

摘要：神经退行性疾病是由神经元和/或其髓鞘的丧失所致，目前该类疾病的病因仍未完全阐明。研究发现，线粒体功能障碍、能量代谢异常, 已成为公认的早期病理现象。本文主要以阿尔茨海默病（Alzheimer’s disease，AD）和帕金森综合症（Parkinson disease，PD）为例，探讨线粒体功能异常在神经退行性疾病发病中的作用，以期为该类疾病诊治和新药研发提供新思路。

中图分类号:

R741

周晓雯, 苏朝芬, 罗焕敏.线粒体与神经退行性疾病[J]. 神经药理学报, 2011, 1(3): 41-46.

Zhou Xiao-wen, Su Chao-fen, Luo Huan-min.Mitochondria and Neurodegenerative Diseases[J]. ACTA NEUROPHARMACOLOGICA, 2011, 1(3): 41-46.

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线粒体与神经退行性疾病

Mitochondria and Neurodegenerative Diseases

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